A novel nano-printing techniques which produces patterns of DNA dots as little as 200nm in diameter holds the potential for genetic assay devices costing less than $50 each.
The new technique called Supramolecular Nano-Stamping (SuNS) uses single strands of DNA on a surface to act as a master for the biding of complementary pairs. The duplicates can be used as masters as well, allowing the process to proceed exponentially while reproducing complex patterns.
In DNA microarrays as many as 500,000 tiny DNA dots are aligned in a known pattern allowing for the quick assessment of complementary pairs when exposed to a patient's DNA sample. This can be used to identify genetic abnormalities, cancer, and even the presence of specific pathogens.
Currently, microarrays cost in the neighborhood of $500 and require as many as 400 printing steps. According to the researchers, microarrays fabricated with the new process could be manufactured far more simply and for as little as $50.
The wide-scale implementation of such a technology would have massive imlpications both for the cost and quality of medical treatment. Despite modern medicines wonders, diagnosis of pathology remains primarily an art relying on the knowledge and training of the physician. A microarray system would allow for quick and precise diagnoses eliminating many of the costly and potentially deadly complications which ensue from diagnostic errors.